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Breast Cancer Awareness Month, ForME , For YOU , For EVERYONE .

Breast Cancer

Breast cancer is the second-most-common cancer among American women, behind only skin cancer (NCCN 2016; U.S. Cancer Statistics Working Group 2017). About 250,000 women in the United States are diagnosed each year (ACS 2017a).
Although breast cancer research receives enormous funding from public and private sectors, much of the money goes toward studies on prevention and early detection. Thus, treatment options for women with breast cancer have not advanced dramatically in some time. Interventions that form the basis of most breast cancer treatment regimens today—surgery, chemotherapy, radiation, and hormone therapy—were fine-tuned from the 1980s into the early 21st century, leading to marginal outcome improvements. However, few true breakthroughs have emerged (Zurrida 2015).
But promising recent research may soon change the breast cancer treatment paradigm. For instance, immunotherapy—in which the body’s immune system is leveraged to fight cancer—has dramatically improved treatment options for other types of cancer, and results from early trials in breast cancer are promising (Solinas 2017). Many immunotherapy clinical trials are underway, paving the way for this new frontier in cancer treatment, and women with breast cancer may be able to participate in this research.
Other advances in breast cancer diagnosis and treatment are emerging as well. For instance, Oncotype DX and MammaPrint are two recently developed tests that check for molecular changes in tumor tissue and help patients and their medical team fine-tune their treatment plans (Nicolini 2017; Gyorffy 2015).
In addition, intriguing findings suggest off-label use of some cholesterol-lowering statin drugs (including atorvastatin, lovastatin, and simvastatin) may improve chances of survival for women with breast cancer (Liu 2017). And the first-line anti-diabetic drug metformin has shown some promising effects in breast cancer patients, even among non-diabetics (DeCensi 2015; Ko 2015).
Furthermore, several natural interventions and dietary considerations may benefit women with breast cancer (Li 2017). For instance, above-average dietary intakes of selenium, omega-3 fatty acids, or lignans have been associated with better outcomes in women with breast cancer (Harris 2012; Khankari 2015; McCann 2010), and drinking more than three cups of green tea per day has been associated with reduced breast cancer recurrence (Bao 2015).
In this protocol, you will first learn how breast cancer is typically detected and treated. Next, you will learn about compelling novel and emerging treatment strategies currently being tested in clinical trials. The latest recommendations and research on dietary and lifestyle considerations are summarized, highlighting the value of exercise and a diet rich in fruits and vegetables (Heitz 2017; Runowicz 2016). Lastly, you will learn about natural interventions that may improve the body’s ability to fight this disease and manage side effects of conventional treatments (Sinha 2017; Zhang, Haslam 2017; Limon-Miro 2017; Yao 2017).
Note: this protocol should be reviewed along with other relevant, cancer-related protocols:
October 4, 2018 / by / in , , ,
The latest advances in health and longevity Is?

 

 

Eating just once a day associated with longer life in mice

Eating just once a day associated with longer life in mice
Life Extension Health Concens
September 7 2018. An article published on September 6, 2018 in Cell Metabolism reported the finding of researchers from the National Institute on Aging (NIA), the University of Wisconsin-Madison, and the Pennington Biomedical Research Center in New Orleans of a longevity benefit for once- per-day feeding in male mice.
Two hundred ninety-two mice were divided to receive one of two diets. One diet was naturally-sourced and was lower in fat and added sugar and higher in protein and fiber than the other diet. Each group was divided into three subgroups that received unlimited access to food, 30% fewer calories than the first group, or one meal per day that contained the same number of calories consumed by the first group.
Calorie-restricted mice and mice fed once daily survived longer than the animals who ate as much as they liked and experienced delays in the development of age-related damage to the liver and other organs. Diet composition was not found to affect the lifespan of these groups.
“This study showed that mice who ate one meal per day, and thus had the longest fasting period, seemed to have a longer lifespan and better outcomes for common age-related liver disease and metabolic disorders,” reported NIA Director Richard J. Hodes, MD.” “These intriguing results in an animal model show that the interplay of total caloric intake and the length of feeding and fasting periods deserves a closer look.”
“Increasing daily fasting times, without a reduction of calories and regardless of the type of diet consumed, resulted in overall improvements in health and survival in male mice,” concluded lead researcher Rafael de Cabo, PhD. “Perhaps this extended daily fasting period enables repair and maintenance mechanisms that would be absent in a continuous exposure to food.”
—D Dye
SOURCE : Life Extension What’s Hot Archive September 2018

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September 24, 2018 / by / in ,
Do You Have Allergies ?

Take care of your body. It’s the only place you have to live. Jim Rohn
 
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Allergies

allergies
LifeExtension.com
Allergies are a global public health menace (Pawankar 2011). More than 500 million people worldwide suffer from food allergies. More than 300 million, or about 5% of the global population, now suffer from asthma(Chang 2011). Allergic rhinitis, a risk factor for asthma, affects up to 30% of adults and 40% of children (Wallace 2008).
Some scientists theorize that a potential cause of allergies in the modern world may be over-sanitation. Excess utilization of antibiotics and less frequent exposure to microbes like bacteria and viruses during childhood may impair development of balanced immunity, causing hyper-reactivity to allergens later in life, a phenomenon known as the hygiene hypothesis” (Fishbein 2012; Jedrychowski 2011).
Relieving allergy symptoms in hopes of improving quality of life is the primary goal of treatment. However, patients often report that their conventional medications fail to provide relief (Li 2009; Metcalfe 2010). Also, corticosteroids and beta-2-agonists, drugs frequently used to treat allergic asthma, are fraught with potentially deadly side effects over the long-term.
Reliable allergy testing methods allow for a more guided treatment approach that includes identification and avoidance of troublesome allergens, as well as targeted immunotherapy with allergy shots, or via sublingual immunotherapy – an effective method underutilized in the United States, but which has been employed in Europe for decades (Lin 2011).
When you read this protocol, you will learn what causes allergies, how medical treatment can help relieve allergic reactions, and how allergy testing strategies can empower you to significantly reduce your allergic symptoms by identifying and avoiding the dietary or environmental culprits driving them. You will also read about several natural compounds with immunomodulatory properties that quell allergen-induced inflammatory responses to provide symptom relief.

What is an Allergy?

An allergy occurs when your immune system responds aggressively to a harmless environmental substance.
Common inhaled allergens include tree and flower pollen, animal dander, dust, and mold. Ingested allergens include medications (penicillin, for example) and foods such as eggs, peanuts, wheat, tree nuts, and shellfish. Nickel, copper, and latex can also cause allergies (AAAAI 2011; Kasper 2005).
These allergens can affect various parts of the body and elicit symptoms in the nasal passages (such as itchy, stuffy and/or runny nose, postnasal drip, facial pressure and pain); mouth area (tingling sensation, swollen mouth and lips, itchy throat); eyes (swollen, itchy, red eyes); respiratory (wheezing, coughing, difficulty breathing, shortness of breath); skin (hives, rashes, swelling); and gastrointestinal (stomach cramps, vomiting, diarrhea). Symptoms can occur within minutes to days after exposure and can range from mild to severe.
The most severe form of allergic reaction is called anaphylaxis. It is a potentially deadly condition that results in respiratory distress and swelling of the larynx, often followed by vascular collapse or shock (Kasper 2005). Anaphylaxis should be treated rapidly because death can occur within minutes or hours after the first symptoms appear. Many people prone to anaphylaxis carry self-injecting epinephrine pens in case of emergencies.

What Causes an Allergic Response?

The immune system normally functions to protect the body against viruses, bacteria, fungi, and other pathogens by targeting these substances for destruction upon recognition. However, an allergic response arises when your immune system mistakes harmless substances as potential pathogens and attacks them .Read more here 
SOURCE :  LIFE EXTENSION

March 31, 2018 / by / in ,
How To Stay Motivated Fit This Year !

“We are what we repeatedly do. Excellence then is not an act but a habit.” —Aristotle

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Never give up on a dream just because of the time it will take to accomplish it. The time will pass anyway. – Earl Nightingale.

January 8, 2018 / by / in
I Do Not Remeber

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Alzheimer’s disease is a neurodegenerative disorder characterized by a decline in cognitive function that eventually leads to death (Upadhyaya 2010; Stern 2008; Knopman 2012; Mayo Clinic 2011). Research in Alzheimer’s disease has not yet identified a cure for the disease. Advanced age is a risk factor for development of the disease (Alzheimer’s Association 2012b; Knopman 2012).With an increase in the aging population, the worldwide prevalence of Alzheimer’s disease has increased remarkably and is expected to continue to do so. Estimates suggest that in the United States alone there will be 11-16 million individuals aged 65 and older diagnosed with Alzheimer’s disease by 2050 (Zhao 2012; Tarawneh 2012).Alzheimer’s disease appears to be the consequence of several convergent factors including oxidative stress, inflammation, mitochondrial dysfunction, and accumulation of toxic protein aggregates in and around neurons (Luan 2012; Teng 2012; Rosales-Corral 2012; Wang 2007; Fonte 2011; Ittner 2011). Emerging, intriguing research implicates chronic infection with several pathogenic organisms in the development and progression of Alzheimer’s disease as well (Miklossy 2011). Moreover, age-related changes such as declining hormone levels and vascular dysfunction are thought to contribute to some aspects of Alzheimer’s disease (Vest 2012; Barron 2012; Baloyannis 2012).Conventional pharmacologic interventions target symptoms, but fall short of addressing underlying, contributing factors for Alzheimer’s disease. This results in a small reduction of symptoms, but does not halt or reverse disease progression (Sadowsky 2012; Alkadhi 2011).A comprehensive approach to Alzheimer’s disease treatment is required that acknowledges and targets the many possible factors underlying the changes in brain structure and function that drive this complex condition (Sadowsky 2012).read more 
Source : Alzheimer’s Disease – Neurodegenerative Disorder, Cognitive Function – Life Extension Health Concern

April 18, 2017 / by / in